Sugashima Marine Biological Laboratory (MBL) was founded in 1939 as a facility attached to the Nagoya Imperial University School of Medicine.  In 1942 this facility became attached to the newly founded School of Science.  Renovations were carried out in 1971.  In 1996, a new building (Research Building 2) was built. Since marine biota is very variable, Sugashima Island was selected as the location for the MBL. From fiscal year 2013 to 2017, this facility was authorized by MEXT as an educational center for advanced marine biology.  The MEXT authorization was recently renewed for an additional five years, from 2018 to 2022.  About 4,000 scientists and students utilize this facility every year.  Three boats are available for use at this MBL:  Aster (4.6 tons, for 30 persons), Frontier (4.6 tons, 13 persons), and Prajna (0.7 tons, 6 persons). There are many research instruments for biochemistry, molecular biology and cell biology research, including an LC/MS, DNA sequencer, and various microscopes. Summer and Spring Courses for Marine Biology are also available for the undergraduate students of the Division of Biological Sciences in this university. In addition, Marine Biology Courses are available for undergraduate and graduate students from universities other than Nagoya University, for foreign students, and for senior high school students.

Biological studies on fertilization and early development in marine invertebrates, such as sea urchins and ascidians have been carried out at this marine biological laboratory. Current research activity is mainly focused on the fertilization mechanisms of ascidians and sea urchins and on the mechanisms of allorecognition, or self-sterility during fertilization of ascidians.

In this laboratory, the mechanisms of hemorrhage and apoptosis of endothelial cells inducted by ADAM-family toxin VAP (vascular apoptosis-inducing protein from hemorrhagic snake venoms) have also been investigated.

address:429-63 Sugashima, Toba, Mie Prefecture 517-0004,Japan